QUESTION 25 (3 marks)
In blood group inheritance in humans, three alleles (i, IA and IB) determine blood type, which can be type O, A, B or AB. It is known that:
• allele IA produces type A and is co-dominant with allele IB, which produces type B
• allele i produces type O
• alleles IA and IB are dominant over allele i. A father who is heterozygous type A and a mother who is heterozygous type B have children. Predict the likely frequency of phenotypes for their offspring. Show your working.
QCAA guide · typeset solution
QCAA sample response and mark allocation
25 | The genotypes of the parents are IAi and IBi Potential crosses IA i IB IAIB IBi i IAi ii 1⁄4 type AB, 1⁄4 type A, 1⁄4 type B, 1⁄4 type O | • identifies parents as IAi and IBi [1 mark] • shows appropriate working [1 mark] • states a consequentially correct frequency for each blood type [1 mark] |
QCAA sample response and marking criteria reproduced from the official guide.
Compare your working with the guide above.